Please note: packaging may differ from one shown What is NO2 Extreme? Endothelial cells can be found on the inner surface of blood vessels and are responsible for the reaction that produces nitric oxide from L-Arginine. Once produced nitric oxide can diffuse into the nearby vascular smooth muscle, promoting relaxation and subsequently vasodilation. This allows for increased blood flow which can be beneficial when training, since your blood transports oxygen and nutrients. L-Arginine is not produced endogenously, and so must be consumed via diet. NO2 Extreme combines Arginine Alpha-Ketoglutarate (AAKG) with Arginine Ethyl-Ester HCL (AEE) along with Alpha-Ketoglutarate (OAKG). This product also contains niacin. Our NO2 Extreme is a revolutionary approach to amino acid based NO promotion. NO2 Extreme Benefits NO2 Extreme provides an excellent source of L-arginine and is conveniently dosed in capsules for your ease of use. Furthermore, our recommended use directions provide 4.5mg of niacin daily which contributes to normal energy-yielding metabolism and to the reduction of tiredness and fatigue. Who is NO2 Extreme suitable for? NO2 Extreme is recommended to anyone looking to get the most out of their training regime and particularly to those doing high-intensity strength workouts. This product may also be suitable looking to increase their dietary intake of L-Arginine. Please note that the labelling on this product is provided in English as a minimum. French, Italian, German, Spanish, Danish, Swedish and Finnish may also be present on a product by product basis.